the medical science that supports common cbd claims about reducing pain inflammation and anxiety
Yes, we’re open. SAVE 20% with code ‘my20’
Medical research supporting CBD claims about reducing pain, inflammation & anxiety.
Cannabidiol (CBD) is one of over 60 cannabinoids found in the cannabis plant and the basis of many claims implicating its ability to help relieve things like pain, anxiety and inflammation.
CBD is certainly not a cure-all for every condition but there are many valid studies supporting its ability to affect and support users in a positive regard. Research on authoritative channels such as PubMed reveals useful data regarding CBD and its role in many human conditions.
CBD’s ability to positively affect these symptoms is discussed frequently and often casually, leaving many consumers and professionals searching for more data supporting these claims. Here are some of the ways CBD works in the body to affect and support key conditions, explained with science and relatable examples:
PAIN
CBD has been shown to interact with TRPV1 receptors. [1] [2]
TRPV1 receptors have many roles, but are involved with pain perception, inflammation and many other processes. TRPV1 receptors are found throughout the body in the peripheral nervous system’s pain receptive neurons.
The interaction of CBD with these TRPV1 receptors suggests that it has the ability to help mediate pain signaling. The TRPV1 signaling process is designed to protect you from danger but they operate in a non-intuitive way through a process of desensitization; they don’t remove the pain, but rather they reduce the pain signal.
For example, have you ever eaten a hot pepper and felt pain from “heat” in your mouth? The capsaicin in the peppers activated the TRPV1 receptor. The heat was uncomfortable in your mouth but then over time felt like you got used to it. However, it was actually the TRPV1 receptors that became desensitized, reducing the discomfort; it wasn’t the pain or heat dissipating.
Pain from hot water heat at around 109F can also activate the TRPV1 receptors. For example, when you step into a hot shower it may feel unbearably hot at first but becomes more tolerable moments later as the TRPV1 receptors are activated and begin to signal the pain you feel a little less. The result is that you feel less pain and your heat-induced threshold is elevated, even though the water is still hot.
INFLAMMATION
CBD has been shown to increase adenosine levels, which plays a role in helping with inflammation and has been well studied. [3] [4] [5]
Adenosine is known to mediate (reduce) recruitment of white blood cells to sites in the body experiencing inflammation. In some instances, white blood cell activity in an inflamed area can lead to discomfort.
This is how it works: CBD interacts with and limits adenosine reuptake (a normal process for neurotransmitters) resulting inelevatedlevels of adenosine. Elevated adenosine levels create a reduction in white blood cell activity at the inflamed site. And when there’s a reduction of white blood cell activity at the inflamed site, a reduction in inflammation can occur – and therefore a reduction in pain. It’s for this very reason many people take NSAIDS (nonsteroidal anti-inflammatory drugs) such as aspirin and ibuprofen, which affect inflammation through a similar white blood cell reduction.
Adenosine also plays a role as a vasodilator (increased blood flow) to various organs in the human body. Given that CBD can elevate adenosine levels, there may also be (yet to be studied) associations to increased blood flow elsewhere in the body and possibly the genitals – which would be seen as very positive in the sexual wellness and pleasure space.
ANXIETY
CBD targets GABA-A receptors. [6] [7] [8]
GABA is an amino acid that acts as a neurotransmitter in your brain and acts as a brake to the excitatory neurotransmitters. When bound, it produces a calming effect by inhibiting certain signals.
CBD is a positive allosteric modulator of the GABA-A receptor. It changes the shape in a way that increases its natural binding affinity with GABA, resulting in anxiety reduction.
If you are familiar with Valium, then you are familiar with GABA-A receptors. Valium (Diazepam) targets GABA-A receptors and is commonly used for treatment of anxiety and insomnia. CBD operates in a similar manner, resulting in the commonly reported anxiolytic (anxiety reducing) effect.
Alcohol is one of, if not the most, commonly used anxiety and inhibition reducing drugs used prior to intimacy. It’s why 1 in 4 women like to drink before sex and 1 in 7 women say they can’t have sex with their significant other without drinking, according to a 3,000-person survey. [9]
Reducing anxiety in the bedroom, and with a natural plant-based remedy like CBD has obvious benefits for your health, intimacy and sexual wellness.
SUMMARY
Reports of cannabidiol benefits are rampant on the Internet. Many are well founded, others are questionable. cbd beauty It is refreshing to now see detailed and authoritative studies supporting many of the claims that are made, however some of the research is associative; if A effects B and B affects C, then A must affect C.
But with widespread consumer interest in CBD, we can only expect that more studies detailing specific risks and benefits will be executed. Funding for cannabinoid research is increasing and federal positions are relaxing, which will lead to more research and a better understanding of cannabidiol and how other cannabinoids interact with our bodies’ endocannabinoid system to provide therapeutics effects.
As for decreasing pain, anxiety and inflammation— achieving new levels of comfort in these key areas can only lead to better and more frequent sexual activity for both women and men.
—
[1] Fonseca, B. M., Correia-Da-Silva, G., & Teixeira, N. A. (2018).Cannabinoid-induced cell death in endometrial cancer cells: involvement of TRPV1 receptors in apoptosis.Journal of Physiology and Biochemistry, 74(2), 261–272. doi: 10.1007/s13105-018-0611-7
[2] Kossakowski, R., Schlicker, E., Toczek, M., Weresa, J., & Malinowska, B. (2019).Cannabidiol Affects the Bezold-Jarisch Reflex via TRPV1 and 5-HT3 Receptors and Has Peripheral Sympathomimetic Effects in Spontaneously Hypertensive and Normotensive Rats. Frontiers in Pharmacology, 10. doi: 10.3389/fphar.2019.00500
[3] Mecha, M., Feliú, A., Iñigo, P., Mestre, L., Carrillo-Salinas, F., & Guaza, C. (2013).Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors.Neurobiology of Disease, 59, 141–150. doi: 10.1016/j.nbd.2013.06.016
[4] Burstein, S. (2015).Cannabidiol (CBD) and its analogs: a review of their effects on inflammation.Bioorganic & Medicinal Chemistry, 23(7), 1377–1385. doi: 10.1016/j.bmc.2015.01.059
[5] Council, E. (2019). Cannabidiol Reduces Inflammation: A Narrative Review.https://cbdhoustonllc.com/wp-content/uploads/2019/10/Cannabidiol-Reduces-Inflammation.pdf
[6] Bakas, T., Nieuwenhuijzen, P. V., Devenish, S., Mcgregor, I., Arnold, J., & Chebib, M. (2017).The direct actions of cannabidiol and 2-arachidonoyl glycerol at GABA A receptors.Pharmacological Research,119, 358–370. doi: 10.1016/j.phrs.2017.02.022
[7] Blessing, E. M., Steenkamp, M. M., Manzanares, J., & Marmar, C. R. (2015).Cannabidiol as a Potential Treatment for Anxiety Disorders.Neurotherapeutics,12(4), 825–836. doi: 10.1007/s13311-015-0387-1
[8] Shannon, S. (2019).Cannabidiol in Anxiety and Sleep: A Large Case Series.The Permanente Journal. doi: 10.7812/tpp/18-041
[9] September 29, 2009 by P. #https://www.justcbdstore.com# The Best CBD CREAMS from JustCBDN. S. S. (n.d.). Three of Four Women Drink Before Sex, Survey Finds. Retrieved fromhttps://drugfree.org/learn/drug-and-alcohol-news/three-of-four-women-drink-before-sex-survey-finds/
GoLove
Service
GoLove CBD Naturals
Created by CBD scientist John Renko & sexologist Dr. Sadie Allison, GoLove CBD lube soothes the body & mind, so you can enjoy more comfortable, pleasurable sex.
© 2020GoLove CBD Naturals.
All rights reserved. Theses statements have not been evaluated by the FDA. This product is not intended to diagnose, cure or prevent any disease.
We use cookies to give you the best shopping experience. By using this site, you agree their use.
Looking for Something?
Our physicians are leaders within the medical business. Dedicated to enhancing the health of others, our physicians are committed to education, research, and well being promotion. We are devoted to offering leading edge medical providers whereas remaining respectful of cultural, linguistic, and spiritual range, and guarantee thorough care by facilitating helps for many who want continuing care. Health care in India, China, Russia and Africa is offered to these areas’ huge rural areas by mobile health clinics or roadside dispensaries, a few of which combine conventional medicine. In India these traditional clinics provide ayurvedic medicine and unani herbal medical follow.
All email entrepreneurs know that optimizing e mail advertising campaigns is an ongoing, exhaustive course of. Follow concrete steps, similar to those outlined above, to help you not only hold your adverse metrics low, but additionally make certain your e mail subscriber base is healthy and excited to receive your content material of their inboxes. By making the expertise as helpful as potential, you possibly can ensure your prospects are looking forward to your presents and data. This re-engagement e-mail attempts to function every thing that an inactive subscriber might have missed.
That stated, the basics of what makes B2B advertising efficient have remained fixed regardless of the medium. There are 
In the dynamic eCommerce setting, it means automating what you can as much as you can. Moreover, B2B clients require extremely customized advertising and sales approaches, which must be also kept in sync at all times. e-mail advertising stands above some other digital advertising strategy by way of ROI.
A segmented e mail subscriber record is crucial to extremely targeted emails. For instance, Bob, the home remodeler, will see significantly better results when he sends his kitchen transforming e-mail campaign only to leads who expressed interest in kitchen remodels, quite than to his entire lead listing. 
The greatest disadvantage to taking a program in-house is the massive capital investment wanted to get a telemarketing program started. It entails hiring and training new personnel, buying new communications gear, and coping with a process that’s unfamiliar to many in enterprise. The industry is still adjusting to the new actuality that has been created by the do-not-call registry. They will continue to search for ways during which to generate new phone lists that embrace potential clients that aren’t on the do-not-name listing or shoppers who by advantage of signing up for a sweepstakes occasion have created for themselves a “relationship” with the vendor. Companies with whom a person has carried out business or with whom an individual has signed up for a drawing are allowed to name that individual whether or not his or her cellphone number is on the do-not-call record.
Our comprehensive Pharmaceutical Mailing list enables you to make easy customer interactions through multi-channel marketing. It helps you schedule and jumpstarts your campaigns with the reputed choice-makers in the pharmaceutical industry. The Lake B2B pharmaceutical manufacturing masterfile is a wonderful marketing database that provides the up to date and verified info on your email, postal, or telemarketing campaigns.
This signifies that you need to establish or keep your seo (search engine optimization), pay-per-click on (PPC) promoting, and social media companies whilst you use show marketing for the most effective outcomes. Online advertising has opened up a world of possibilities for those making an attempt to advertise, significantly to customers in teams which might be very energetic in looking out the web, reading social media and testing varied web sites.
We specialize in offering the biggest number of trade-particular, pre-made B2B Marketing Leads. We have over 10,000 advertising lists masking the all industries and niches. If you promote merchandise or provide services to different businesses, you could use our worldwide area of interest-related email listing to send your promotional emails, newsletters or even do a visitor post outreach for search engine optimization backlink constructing. For example, in case you are a jeweller who makes marriage ceremony rings, you could want to contact all of the jewellery stores and marriage ceremony gown retailers on the planet to offer them to inventory your marriage ceremony rings or collaborate with you. Their advertising associate, Summit Digital Marketing, has been helping them grow their email record and enhance the standard of their leads since March 2018.
Look in native publications for dispensary advertisements, both brick-and-mortar, and supply. This provides you with an concept of the unlicensed operators in your area. Additionally, research crime busts on unlicensed operations in your area.
